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The supplements are widely available and can be found in various forms, including capsules, tablets, and liquid formulations

With respect to definition of controls, most studies recruited healthy children with no information about family history of autism spectrum disorders, although, four studies did ensure that controls did not have either a family history or sibling with autism [70, 75, 77, 87] and one screened for autism traits [59]

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Erujawa et al

Although the pathophysiology of ASD is still poorly understood, the interplay between genetic and environmental factors has been suggested to cause the disease 5