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2015 Apr;15(2):145-50

After prolonged physical exertion, glutathione neutralizes reactive oxygen species (ROS) produced during the Krebs cycle, effectively preventing the lipid peroxidation of mitochondrial membranes and allowing them to recover and maintain efficient ATP production without suffering from premature fatigue or permanent oxidative damage.

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Certain metabolic issues such as insulin resistance, where the bodys cells stop responding properly to insulin, may also block semaglutides actions