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Additionally, topiroxostat inhibits the ATP-binding cassette transporter G2 (ABCG2), which plays a key role in renal uric acid reabsorption and the secretion of uric acid from the intestines

Liver health support: May reduce fat buildup in the liver, a common complication of excess weight

The drugs, which contain the active substance semaglutide, work by mimicking a hormone called glucagon-like peptide-1 (GLP-1), which reduces appetite, leading to weight loss

Holly Wyatt: So tell us, you're at the maximum dose, how long have you been on the medication and how much total weight have you lost over that period

It is worth noting that UK clinical guidance recognises lower BMI thresholds for assessing weight-related health risk in some ethnic groups your GP or specialist can advise on how this applies to your individual circumstances